CRIS PROGRAMME OF EXCELLENCE 2019 Researcher: Dr. David Olmos Center: : Centro Nacional de Investigaciones Oncológicas, Madrid Introduction: In developed countries, prostate cancer is the most commonly occurring tumour in males. Generally, most patients are diagnosed in the early stages when the tumour is still localized and are usually cured. However, in 5-10% of patients, diagnosis occurs when the tumour has
Principal Researcher: Dra. Clara Montagut Viladot Center: Hospital del Mar Investigacions Mèdiques Biography: Clara Montagut graduated from the Autonomous University of Barcelona with a degree in Medicine and Surgery and trained in medical oncology at the Hospital Clínic. She specialized in translational cancer research, specifically in biomarkers and mechanisms of resistance to biological drugs at the Hospital Clínic itself and at the Massachusetts General Hospital Cancer Center (Harvard
Project Directores: Dr. Luis Paz-Ares, Dr. Luis Álvarez-Vallina. Centres: Hospital Universitario 12 de Octubre de Madrid, Centro Nacional de Investigaciones Oncológicas (CNIO). Introduction During the last few years, the conception of how cancer develops has changed radically. Tumours are no longer considered isolated entities that grow in isolation from their environment, and it has been
Principal Researcher: Dr. Miguel Ángel Quintela Center: CNIO, Madrid Introduction: Breast cancer is the most common cancer in the UK. Around 55,200 people are diagnosed with breast cancer every year in the UK. That is around 150 people a day. 15 out of 100 (15%) of all newly diagnosed cancers in the UK are breast cancer. It is
Principal Investigator: Dra. Mª Elena Élez Centre: Vall d’Hebrón Institute of Oncology (Barcelona) Introduction: There are around 42,300 new bowel cancer cases in the UK every year, that’s more than 110 every day. Bowel cancer is the 4th most common cancer in the UK, accounting for 11% of all new cancer cases. It is also the 2nd
Introduction: The CRIS Unit comprises three facilities, which have been set up to undertake the three most important phases in the development of new therapies, primarily: Translational Oncology Laboratory: studies are carried out in this laboratory to identify new targets and therapeutic strategies. New Compound Screening Laboratory: once new therapeutic strategies have been designed, the process of testing a large number of drugs or compounds is started. Using high-performance techniques, those with the greatest
Principal Investigator: Dr. Enrique Grande Centre: Fundación MD Andersen Center, Madrid Introduction: Bladder cancer is a relatively common tumour, with an estimated 10,233 new cases a year in the UK. It is more common with ageing, with 70% of cases occurring in patients over the age of 65 years. It is a type of cancer that is often
principal investigator: Dr. Mariano Barbacid Center: Centro Nacional de Investigaciones Oncológicas (CNIO) Context: Pancreatic ductal adenocarcinoma accounts for 90% of malignant pancreatic tumours. It poses a massive medical challenge for a variety of reasons. Firstly, it is one of the most aggressive and fastest spreading tumours from which a staggering 95% of patients do not survive. Secondly, it is generally diagnosed late and, as there are also no effective treatments for it, mortality rates are extremely high. Pancreatic cancer is the 10th most common cancer
One of the most promising avenues of research in the quest for new ovarian cancer treatments is the manipulation of the immune system, namely Immunotherapy. The project’s current focus is on various aspects of this type of therapy. Several projects are currently being developed that focus on the immune system as a gateway to better therapies.
Principal Investigators: Dr. Silvia Sánchez Ramón, from the Immunology Service, with the collaboration of Dr. Alberto Ocaña and Dr. Pedro Pérez Segura from the Medical Oncology Service and CRIS UNIT for New Experimental Therapies Centres: Hospital Clínico San Carlos. Current situation SARS-Cov-2, the coronavirus that has led to the COVID19 epidemic, has marked a turning